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These include: Nausea (affecting 2040% of users, usually improving over time) Vomiting, diarrhoea, and constipation Abdominal pain and bloating Reduced appetite (intended effect, but can be excessive) Less common but more serious adverse effects include pancreatitis (inflammation of the pancreas), gallbladder problems including gallstones, and hypoglycaemia (particularly in people also taking diabetes medications)