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Braidy N, Grant R, Brew BJ, Adams S, Jayasena T, Guillemin GJ
Current clinical-trial and FDA materials provide additional topical, compounding, and regulatory context [9] [10] [11] [12]
The administration of high doses of lipoic acid by injection to rats decreased the activity of two biotin-dependent enzymes by about 30%-35% (122), but it is not known whether oral or intravenous lipoic acid supplementation substantially increases the requirement for biotin in humans (123)
Bulletin of Experimental Biology and Medicine, 135(6), 590592
10.1016/j.oooo.2022.08.004 5 AlrawiS
So I kept it dead simple
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