Garvey WT, Frias JP, Jastreboff AM et al (2023) Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial
Reduced Appetite: Acts on receptors in the brain regions controlling appetite, leading to decreased hunger and a diminished desire to eat
1 The most frequently reported adverse events were nausea, diarrhea, vomiting, constipation, and abdominal pain
Hot flushes are not listed as a recognised side effect in official UK prescribing information, though some patients report experiencing them
Staying Physically Active Engage in at least 150 minutes of moderate exercise per week
The Triple Receptor Mechanism Explained Understanding how Retatrutide works requires examining each of its three receptor targets individually before appreciating how they combine for enhanced effect