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Watch for additive serotonin effects if combined with behaviour drugs (see notes)

3 RGN-259 Phase 3 Trial in Neurotrophic Keratopathy Sosne et al., International Journal of Molecular Sciences (2022) This Phase 3 randomized, placebo-controlled, double-masked clinical trial evaluated topical 0.1% RGN-259 (full-length recombinant T4 ophthalmic solution) in patients with neurotrophic keratopathy

The active component turned out to be the tripeptide glycine-histidine-lysine, which binds copper to form GHK-Cu

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2023, www.fda.gov/news-events/press-announcements/fda-approves-new-medication-chronic-weight-management