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Nanoparticle-based delivery systems have emerged as a promising approach for brain-targeted therapy, provided they exhibit favorable physicochemical and safety profiles (Masserini 2013)

10.1080/0886022x.2024.2354918 83 TianY.ZhouC.YanQ.LiZ.ChenD.FengB.et al (2025)

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doi: 10.1016/j.envint.2017.12.033

Once inside the mitochondrial matrix, Carnitine Palmitoyl Transferase 2 (CPT 2), located on the inner mitochondrial membrane, converts acylcarnitines back into acyl-CoAs and free carnitine

Post incubation, the liberated IGF-1 was co-immunoaffinity extracted with the internal reference, using protein A/G MSIA pipette tips (from Thermo Fisher Scientific) loaded with antihuman IGF-1 antibody