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They're not improving the quality of the food they're eating," Allen said

Key findings from the Phase 2 trial included: Dose-dependent weight loss , with greater reductions observed at higher doses Significant improvements in waist circumference , blood pressure , and lipid profiles Reductions in fasting glucose and insulin resistance markers, though the clinical significance of these findings in people with type 2 diabetes requires further investigation Weight loss appeared to continue throughout the 48-week period without a clear plateau at the highest doses Whilst these results are encouraging, it is important to contextualise them appropriately

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In April 2026, the FDA approved a new glucagon-like peptide-1 receptor agonist (GLP-1 RA)

The two-domain binding mode suggests that the C-terminus of the peptide hormone initiates recognition with the ECD

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