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In a model of lipopolysaccharide (LPS)-induced visceral hypersensitivity and repeated water avoidance stress (WAS) in rats, liraglutide effectively reduced visceral allodynia by suppressing pro-inflammatory cytokine production and improving colonic barrier integrity [59]
Early Parkinsons trials have shown mixed results, and Alzheimers trials are In the intestine and joints, GLP-1 agonists reduce intestinal inflammation in colitis models and may benefit osteoarthritis by reducing synovitis and chondrocyte inflammation
10.1186/s43162-020-00026-9 36 GersteinH
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Toxicology 216 , 197203 (2005)
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