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A 2mg injection delivers far more systemic peptide than 2mg in a topical

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Additionally, glutathione switches melanin synthesis from eumelanin (brown-black pigment) to pheomelanin (red-yellow pigment) by altering the availability of cysteine residues during melanogenesis

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Picone P, Vilasi S, Librizzi F, Contardi M, Nuzzo D, Caruana L, et al