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In the last 50 years, cysteamine has been shown to lighten pigmentation in the skin through several mechanisms 2-4

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Figure 4 Flavonoids, which include flavanols, flavonols, flavones, flavanones, isoflavones, and anthocyanins, also possess DPP-4 inhibitory activityfor instance, the flavonoid-rich fraction of Pilea microphylla displayed antidiabetic efficacy in rats with diabetes generated by a high-fat diet and streptozotocin by lowering DPP-IV

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J Clin Pathol Microbes 1(1):1-6, 2016