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Description

This immunosuppressive effect is driven not just by acidic pH in the TME, but by a combined lactateproton mechanism mediated through MCT1 transporters (65)

What did they get wrong (or right)

In a properly adherent patient on alendronate 70 mg weekly, CTX should fall to below 200 ng/L within 3 to 6 months of starting therapy

"The depletion of stem cells would imply that the graying is permanent, but this has only been shown in mice," Rosenberg says

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