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evidence suggests reduced hedonic eating

These symptoms may require medical attention or a change in your treatment plan

Or antisense oligonucleotides to mtDNA could perhaps bind and prevent mtDNA from activating TLR9 (though delivering to endosomes in immune cells is a challenge)

Chronic use or high doses can strip away that protection, leading to gastric ulcers or reduced kidney function, particularly if you are dehydrated

Three key takeaways Mounjaro and Wegovy both work in a similar way

More research is needed to understand why there is an association between semaglutide and NAION, as well as why results vary for diabetic and overweight groups