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(PubMed) Weir DG, Scott JM

Because a 4.5 mg dose uses about half the reconstituted vial, plan vial supply accordingly

Rather than being featured prominently in the drug labels or side-of-package warnings, he said, the information appears in a section of the label called use in special populations, so prescribers are left to dig through searching for the section on pregnancy where it says clearly the drug should be stopped. In the labels instructions for use, which explain how to store and administer Wegovy and Ozempic, theres also no mention of pregnancy, said Steven Woloshin, who co-leads the Center for Medicine and Media at the Dartmouth Institute, but there is a whole bit about how to protect the Wegovy pen

"Triple-hormone-receptor agonist retatrutide for obesity a phase 2 trial." NEJM

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The addition of GIP receptor activation may help mitigate some gastrointestinal side effects