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dpv displayed a higher slope of 15.47 A M 1 , yielding an area-normalized sensitivity of 309.4 A M 1 cm 2 , strong linearity (R 2 = 0.99), and an LOD of 1.036 M

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Two decades later Joseph von Mering and Oscar Minkowski, two German physicians based at the University of Strasbourg, showed in a dog that the surgical removal of the pancreas, known as a pancreatomy, immediately caused severe and fatal diabetes

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