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GLP-1 has a short half-life of only two minutes, due to renal clearance and endogenous GLP-1 is degraded by the enzyme dipeptidyl peptidase IV (DPP-4) (2022)
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The standard escalation schedule starts at 2.5 mg weekly for four weeks
Mota SI, Pita I, guas R, Tagorti S, Virmani A, Pereira FC, Rego AC (2021) Mechanistic perspectives on differential mitochondrial-based neuroprotective effects of several carnitine forms in Alzheimers disease in vitro model
One study found that after 30 weeks 1 : 0.5 mg dose: Average weight loss of 3.7kg 1 mg dose: Average weight loss of 4.5kg However, individual responses vary significantly
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