Or carefully waiting for the other shoe to drop
2 Dial & inject Turn the dial to the measured dose
& Strek, M
After 40 weeks, all three tirzepatide groups lost 4-12 more pounds, on average, than the semaglutide group and came out with healthier diabetic biomarkers.3 Another example is a massive cohort study of 18,386 patients, which found that tirzepatide patients lost 5-15% more weight than their semaglutide counterparts.4 Tirzepatides superior efficacy correlates with a higher cost compared to semaglutide
An overview table of included studies is available in the Supplementary Material (S1) and online with options to filter the database ( The table includes information on first author and year of publication (1), paper title (2), whether the study was included in the meta-analysis (3) or systematic review (4), a tag indicating whether ghrelin or GLP-1 was investigated (5), specification of the hormonal assessment and/or manipulation (i.e., whether plasma acyl-, desacyl-, total ghrelin, GLP-1 was measured, which substance was administered (if any)) (6), type of reward phase assessed during fMRI (7), type of reward (e.g., food, money, alcohol) (8), and sample population(s) (9)
Thyroid replacement therapy is typically weight-based, so you will need to work closely with your healthcare provider to monitor and adjust your levothyroxine dosage as needed
