WEIGHT EFFECTS OF GLUCAGON-LIKE PEPTIDE-1 Exogenous GLP-1 was soon demonstrated to have other effects of interest in relation to T2DM, most importantly an inhibitory effect on appetite and food intake [9]
Potential role of neuroactive tryptophan metabolites in central fatigue: establishment of the fatigue circuit
Others experience more modest changes
Starting with a low dose, such as 1 mg or 2 mg weekly, and gradually increasing to higher doses like 4 mg, 8 mg, or 12 mg may help reduce these effects
Wegovy is a GLP-1 receptor agonist licensed in the UK for weight management in adults with obesity or those who are overweight with weight-related conditions
Patients with personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2, diabetic retinopathy requiring treatment, or severe gastrointestinal disease require careful medical evaluation before initiation