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J Am Coll Health

The most common are nausea, vomit, discomfort and dizziness

While the liver plays a significant role in systemic glutathione metabolism, the central nervous system (CNS) maintains its own tightly regulated GSH pool, independent of peripheral control (3-4)

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In the SURMOUNT-1 trial, people treated with tirzepatide lost up to 22.5% of their body weight over 72 weeks , making it even more effective than semaglutide (NEJM tirzepatide study)

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