It's a sequence that makes it very long lasting
Most compounds that target tumor metabolism (methotrexate, 5-fluorouracil) fail to distinguish between tumor tissue and rapidly differentiating epithelial tissue (skin, bone marrow), 4,322 whereas therapies targeting the specific amino acid dependence of tumor cells are cell-selective, such as leukemic blasts that are selectively dependent on Asn, the use of bacterial-derived ASNase in pediatric ALL has significantly improved the cure rate
This is probably due to its effect on learning and memory described above
Additionally, older GLP-1 drugs, such as exenatide, have seen a decline in claims since the early 2010s as newer drugs were introduced
This is why they have developed a reputation as a trustworthy peptide vendor
Hepatology (2016) 64:7384