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Mutations in other genes of this pathway (e.g., LEPR , POMC ) also cause monogenic obesity, but the efficacy of bariatric surgery in these patients differs from that in MC4R -deficient patients

Several large-scale trials, including the LEADER and SUSTAIN-6 studies, demonstrated reduced cardiovascular risk in patients at high baseline risk

Gs separates from G and interacts with the transmembrane protein adenylyl cyclase

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The effectiveness and efficacy of Rhodiola rosea L.: a systematic review of randomized clinical trials

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