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Di Giulio AM, Gorio A, Bertelli A, et al

Interestingly, our live-cell imaging results suggest that CCK peptide does not activate robust increases in intracellular Ca 2+ in mouse -cells as it does in pancreatic acinar cells 30 or vagal afferent neurons 29 and in rat islet 21 , and this lack of an effect on calcium influx may explain the inability to stimulate insulin secretion

When deficient, animals can have reduced appetite and growth rates, ill thrift, infertility, and reduced wool and milk production

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doi:10.3390/ijms25031615

Achieving normoglycemia with tirzepatide: analysis of SURPASS 1-4 Trials