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This matters more for injectables than topicals

Other more serious, though rare, risks include pancreatitis, gallbladder disease and potential kidney injury particularly if severe dehydration occurs due to vomiting, the expert cautioned

The technology commercialization and patent application is led by Baylor Licensing Group, the technology transfer office at Baylor College of Medicine, with the mission to maximize the impact of research at Baylor College of Medicine through commercial relationships that lead to agreements to support the development of new products and services that benefit patients and the public.

Another good reason is that some people have quite a strong adverse reaction to methylcobalamin injections

Endocrinology 158: 4139-4151, 2017

Studies have shown that the test is highly reliable (detecting approximately 90% of cases) for diagnosing moderate to severe pancreatitis in cats