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have reported that GLP-1/exendin-4 could ameliorate oxidative stress-induced injury in PC12 cells (182)
also suggested that MT-1 was associated with reduced expression of cyclooxygenase-2 (COX-2), suggesting a potential anti-inflammatory action on cellular processes
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Genetic variations in incretin receptor expression and signaling pathways may contribute to variable treatment response, though this remains an area of active research
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