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Whereas central nervous system (CNS) effects are determined by BBB penetration, ocular efficacy is governed by the traversal of the BRB

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But the same humility that makes us acknowledge these drugs' apparently magical effects should also make us watch carefully for delayed side effects or complications we haven't predicted

Compared with exenatide, lixisenatide is generally well tolerated, with a lower incidence of hypoglycemia, lower immune response at the injection site, and less side effects such as nausea and vomiting

developed supramolecular prodrug nanoassemblies (SPNA) for reactive nitrogen species (RNS)-enhanced chemotherapy (Figure 3D) (Deng et al., 2021)