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8 GLP-1 RAs and DR: What the data show The CDCs Vision and Eye Health Surveillance System estimated that in 2021, there were 9.6 million people (26 percent of those with diabetes) living with diabetic retinopathy in the United States and among them, 1.84 million people (5 percent) living with vision-threatening diabetic retinopathy
Compounding pharmacies must follow strict guidelines, but the lack of consistent FDA oversight means theres no guarantee that the drugs meet the same safety standards as their branded counterparts
Side Effects & Safety Excellent safety profile in topical and subcutaneous use
The condition occurs when blood supply to the optic nerve is compromised, leading to ischemia and damage to the nerve fibers
Decisions made today across manufacturing and commercialisation will determine which companies are best positioned as these therapies move from promise to scale
In future, it is likely that the clinical indications for GLP- 1RAs will expand, with pharmaceutical companies running various drug trials to substantiate a wider array of use cases, such as the reduction of cardiovascular risk and the treatment of chronic kidney disease
