As discussed in the previous section, there are two enzymes of creatine synthesis, glycine amidinotransferase (encoded by the GATM gene ) and guanidinoacetate N -methyltransferase (encoded by the GAMT gene), and one major creatine transporter encoded by the SLC6A8 gene
Look for reduced glutathione (GSH), not oxidized (GSSG)
Doses as high as 2 mg (2,000 g) daily by mouth or 1 mg monthly by intramuscular (IM) injection have been used to treat pernicious anemia without significant side effects (136)
For solid pills and capsules, using a compact supplement case is often the most practical choice
This may occur in a doctors office, clinic, or outpatient facility
These results are consistent with previous findings in the literature [56]