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GLP-1 receptor agonists offer unique benefits, including weight loss and cardiovascular protection, which are not provided by all diabetes medications

Individual Variation Is Enormous Some of my patients on semaglutide lose more weight than others on tirzepatide

The rise in vision loss claims follows a June 2025 JAMA Ophthalmology study linking semaglutide use to significantly higher rates of NAION

Who Should Not Use These Medications Certain health conditions may rule out the use of these medications, and its crucial to discuss these with a healthcare provider

Another study published by Diabetes, Obesity & Metabolism in June 2025 further supported this link, concluding that the five-year risk of developing NAION doubled in patients using GLP-1 drugs compared to non-users

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