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An excisional biopsy was performed and submitted for histopathological study

25 Although data from clinical studies on liraglutide revealed a 7% increase in serum amylase and a 31% increase in serum lipase in patients after four weeks of GLP-1 receptor agonist treatment compared with placebo, the increased levels reverted to normal once therapy was discontinued and did not predict acute pancreatitis onset

Analogs targeting arginase and arginine deiminase, the enzymes involved in arginine depletion, have been developed

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This data comes from animal models and may not translate directly to human physiology