Gaps: dosing, delivery, safety, and large RCTs remain
Use of high dose or multiple NSAIDs increase the risk of gastrointestinal complications up to 10-fold
In fact, adequate B can improve pregnancy outcomes, and deficiency is common if supplementation is not given
This might seem like a low percentage compared to the 1-10% concentrations we have seen in facial products, but the higher concentration can be irritating to more sensitive skin types
That means no implied medical claims, no suggestions regarding personal usage, and clear language about not for human consumption. When labs consolidate their purchases with a trusted provider, it becomes easier to track lot numbers, control for consistency, and maintain clear documentation for internal review
10.3389/fmolb.2022.1080140 70 MilhelmZ.ZanoagaO.PopL.IovitaA.ChiroiP.HarangusA.et al (2025)