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Wexler DJ, Mayberry LS, Nelson LA, Lema-Driscoll J, Flores LC, Malloy M, et al
& Bharali, M
Its typically tender, doesnt spread, and disappears after 24 hours
Improved glucose clearance reduces blood sugar spikes, easing the demand on insulin and supporting healthier post-meal GLP-1 signaling
Some patients experience improved cycle regularity after initial adjustment because their underlying insulin resistance is resolving
Healthcare professionals should evaluate each case individually, considering the temporal relationship between medication initiation and symptom onset, as well as alternative explanations for headache
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