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Visceral fat produces inflammatory cytokines, contributes to insulin resistance, and correlates strongly with cardiovascular disease risk

Weekly agents have a longer half-life, which extends effects on gastric emptying and glycemia

The participants were predominantly white, which limits how broadly the findings can be generalized to other demographic groups

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As treatment progresses, the Wegovy injection cost increases gradually in line with higher prescribed doses

The findings do not automatically extend to people with type 2 diabetes on other regimens, to people without diabetes taking these drugs for weight, or to people taking injectable GLP-1 medications, which were not in this trial