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Expert Rev Clin Pharmacol 14(9):10811089

Within cells, FFAs, either imported from plasma or released from intracellular lipids via cytosolic lipolysis or lipophagy, are mainly oxidized in mitochondria (mitochondrial -oxidation), peroxisomes (peroxisomal -oxidation) and microsomes (microsomal -oxidation)

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In conclusion, phytosterols and alkaloids can disrupt cancer-associated inflammatory and immune escape mechanisms by inhibiting tumor pro-inflammatory responses and enhancing antitumor immune effects, demonstrating potential clinical applications in improving the tumor microenvironment