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According to FDA prescribing information, fatigue occurs in approximately 11% of patients taking Wegovy and 5-9% of patients taking Saxenda
whether the material is AOD9604 free base, acetate, another salt, hGH 177191, AOD9401, or another related fragment
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Product Specifications Detailed Mechanism of Action AOD-9604 is designed to replicate the lipolytic C-terminal tail of growth hormone while excluding the sequence regions responsible for IGF-1 elevation and insulin antagonism
Increases in resting heart rate are a recognised class effect of incretin-based therapies and have been reported with GLP-1 receptor agonists more broadly, as reflected in the Summary of Product Characteristics (SmPC) for licensed agents such as semaglutide (Wegovy) and liraglutide (Saxenda)
