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Hypothalamic substrates of reward

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Over 40% of new drug approvals now carry orphan designations, up from approximately 15% in 2000 [33]

Radioactive iodine (RAI) is a common treatment for an overactive thyroid (hyperthyroidism)

New or worsening symptoms such as visual changes, severe headache, or signs of thyroid nodules (neck mass, difficulty swallowing) warrant evaluation