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doi: 10.1007/s00464-020-07555-y 20 WildingJPHBatterhamRLCalannaSDaviesMVan GaalLFLingvayIet al

The frequency and intensity of the side effects vary from patient to patient, says Marlena Klein, DO , a board-certified physician in internal medicine

First introduced as a treatment for Type 2 diabetes and now pursued as a blockbuster weight management therapy, GLP-1 receptor agonists (GLP-1 RAs) have ignited a global scale-up effort that is reshaping the drug manufacturing landscape

Compounded semaglutide products are not FDA-approved, so patients should ask where the medication comes from and how dosing is supervised

Another author, Prof Franois Venter from Witwatersrand University in Johannesburg, said: Drugs to treat HIV, TB, malaria and hepatitis are available in low- and middle-income countries for prices close to the cost of production, saving millions of lives while allowing generic companies to make sufficient profit to ensure sustainable supply

Slightly more than half (53%) said they require patients to try non-pharmacological approaches before prescribing GLP-1/GIPs