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The challenge is that we don't have so much data in type 2 diabetes and gestational diabetes

multiple short exposures compound degradation following first-order kinetics

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Muscle that is lost and not recovered has downstream consequences: a slower metabolic rate, reduced insulin sensitivity, weaker bones, and declining physical function over time

While E2 has been shown to increase the effects of metabolic hormones such as insulin, leptin or GLP-1, it is important to remember that ghrelin exerts opposite, orexigenic effects

Used as a pharmacological tool to dissect melanocyte signaling pathways and study disorders of pigmentation