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Most people do semaglutide injections once a week, and the abdomen, thigh, or upper arm are the most common injection sites

The intensity and duration of these effects vary widely between individuals and can influence both tolerance and adherence over time

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Abbreviations: AUC: area under the curve

Almost all the healthy volunteers ended up with profuse vomiting after a single injection of liraglutide!' Fortunately the next study proved more encouraging (Holst 2024)