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Persistent constipation should be reviewed, especially if it affects eating, sleep, work, or comfort
A longstanding unmet need in the care of T2DM and obesity has been to identify therapies that deliver effective glycemic control and clinically meaningful weight loss without increasing cardiovascular risk or severe hypoglycemia
Cheaper alternatives to Wegovy for chronic weight management include FDA-approved prescription drugs like Adipex-P, Ozempic (primarily used to treat diabetes), Xenical, Bontril PDM, diethylpropion, and Saxenda
References Sikiric P, Seiwerth S, et al
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Add in the nausea-driven avoidance of drinking, and you have a recipe for chronic mild dehydration that compounds over weeks
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