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Alterations in cerebrospinal fluid DSIP levels have also been noted in models of depressive behavior, supporting further exploration of its role in mood-related research

Brooks (1) , [email protected] Page 146 and 147: Bordn (2)

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Contraindications Do Not Use If You Have uncontrolled hypertension Have known cardiovascular disease Have a history of hypersensitivity to bremelanotide or any component of the formulation Are pregnant or planning to become pregnant Warnings and Precautions Transient increase in blood pressure and decrease in heart rate: Bremelanotide causes a transient increase in blood pressure (average of 1.9/1.7 mmHg systolic/diastolic, with larger increases in some patients) and a decrease in heart rate following administration