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Competing interests None declared

GLP-1R action on brown adipose tissue (BAT) thermogenesis In addition to causing changes in feeding, central GLP-1R activation may regulate body weight by increasing brown adipose tissue (BAT) thermogenesis (reviewed in Lockie et al., 2013)

Stymulacj angiogenezy wspomaganie procesu tworzenia nowych naczy krwiononych, co przekada si na lepsze ukrwienie i szybsze gojenie uszkodzonych rejonw

-24% body weight documented over 24 weeks in Phase 2 trials

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So how did we get from GLP-1 for diabetes to GLP-1 for weight loss