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1999;26:S36-42
Giles FJ, Faderl S, Thomas DA, Cortes J, Jeha SS, Garcia-Manero G, Douer D, Levine AM, Estey EH, Beran M, OBrien S, Koller C, Andreeff M , H: K
DOI: 10.1038/s41467-017-01114-1 Formulation strategies for therapeutic peptide stability pH, ionic strength, co-solvency
This is among the more speculative areas of research
In addition, berberine is small in size, so it can available through the blood-brain barrier and effectually act on molecular target, showing great therapeutic potential in the treatment of neurodegenerative diseases (Wang et al., 2005