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Milestones in the history of diabetes mellitus: the main contributors

Owing to the rapid reaction between superoxide anions and NO, these so called kindling radicals would lead to the production of ONOO , followed by eNOS uncoupling and subsequent eNOS-mediated superoxide production (bonfire radical, see Figure 2)

The cells were subsequently treated with DCFH-DA (10 M, Bio-lab) for 1 h in the dark, and washed three times with PBS

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SMPDL3B is palmitoylated and stabilized by ZDHHC5, and its silencing aggravates diabetic retinopathy of db/db mice: activation of NLRP3/NF-B pathway

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