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Description

Modulation of CCR2 in Rheumatoid Arthritis: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial

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Through TGR5 receptor activation, it inhibits STAT3/NF-B/MAPK pathway activation, reduces pro-inflammatory cytokine release, and improves cardiac function parameters at 100 mg/kg doses (Wang et al., 2025)

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Initial studies in animal models suggested that pineal peptide extracts containing the AEDG sequence might extend lifespan and improve various markers of aging

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