In research discussions, it is commonly grouped with ghrelin receptor agonists and growth hormone-releasing peptides, but it is often presented as a more selective compound
However, older GLP-1 medications like dulaglutide and liraglutide still produce clinically meaningful outcomes, often with extensive real-world experience and well-characterized safety profiles
Other research highlights: 30% of GLP-1 users tested positive for SIBO or IMO even after accounting for diabetes (5) GLP-1 medicines caused microbiome changes and altered metabolism in mice (6) GLP-1 medicines tested in humans only had noticeable microbiome changes by 48 weeks (7) Despite not necessarily having slower gut motility, one study found that 88.9% of obese patients had SIBO (8) A meta analysis of people with IBS symptoms, found that up to 78% of people had SIBO, many of whom were undiagnosed (9) Overall, Sun and colleagues (1) could not prove a mechanistic link between GLP-1 medications and SIBO, however they did find that SIBO was twice as likely in GLP-1 users
How often we test depends on the patients health and how they react to treatment
Still Deciding
Here are some of the nutrients found in garlic according to the USDA