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In Phase 2 trial imaging, fat mass fell substantially more than lean mass, so most of the weight lost was fat the muscle loss is real but is a minority of total loss and is in the same range as semaglutide and tirzepatide

However, human clinical trials remain scarce

Turn the vial upside down and slowly pull the plunger to your prescribed dose

doi:10.1073/pnas.91.4.1234

The glucose-dependent nature of this effect reduces the risk of hypoglycemia

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