Weight continues declining through week 48 and beyond based on Phase 3 trial data
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Biochemistry 30: 613619 Molteni SN, Fassio A, Ciriolo MR, Filomeni G, Pasqualetto E, Fagioli C, Sitia R (2004) Glutathione limits Ero1dependent oxidation in the endoplasmic reticulum
Sangsuwan W, Asawanonda P
The liver filters out most of the B12 but provides a constant stream in the blood to the rest of the body
Given the known side effects of GLP-1s such as intestinal discomfort and muscle loss, most people have trouble staying on them for more than a year and the weight loss is often reversed once they stop