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The agency says it can have toxic effects on the kidneys, liver, and nervous system

Activated JNK translocates to mitochondria and phosphorylates anti-apoptotic Bcl-2 family members (e.g., Bcl-2 phosphorylation at serine residues such as Ser70) leading to functional inactivation of Bcl-2/Bcl-xL, and promotes pro-apoptotic conformational changes and mitochondrial translocation of Bax (55, 56)

Mohammed, H., Rimondini, L

Always follow the manufacturers instructions and consult a healthcare professional when appropriate

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