Primary outcome and secondary outcomes After a median duration of follow-up for the whole cohort 2.5 years (interquartile range (IQR), 1.43.6 years), 93 patients (2.6%) in the GLP-1 RAs users group and 319 patients (9.0%) in the GLP-1 RAs non-users group experienced all-cause mortality
The most common side effects are mild nausea (usually temporary as your body adjusts), reduced appetite (this is actually the goal!), occasional digestive changes, and fatigue in some patients initially
The SUSTAIN 6 cardiovascular outcomes trial demonstrated that semaglutide significantly reduced the risk of major adverse cardiovascular events (cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke) in adults with type 2 diabetes at high cardiovascular risk, many of whom were taking metformin as background therapy
There is evidence for a cardiovascular benefit of intensive glycemic control after long-term follow-up of cohorts treated early in the course of type 1 diabetes
Most patients were middle-aged (with an average age of approximately 56 years) and overweight or with obesity (with an average BMI of approximately 32 kg/m 2 )
Start your intake How Rapid Weight Loss Increases Gallstone Risk During GLP-1 Therapy Gallstones form when bile cholesterol crystallizes and accumulates in the gallbladdera process accelerated by sudden weight loss