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This novel feature of TNBS to wear off GSH, coupled with its potential for ROS generation, demonstrates that TNBS promotes two independent mechanisms of injury, namely, GSH limitation and ROS accumulation, which in cooperation trigger a chain of processes that lead to cell damage

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Springer: 123

Individuals with Gastrointestinal Disorders Conditions like Crohns disease or celiac disease can impair B12 absorption

However, the two compounds greatly differ in their effects