It says injectable receptor agonists typically show stronger appetite suppression than oral forms, and that dual-action compounds addressing both GLP-1 and GIP pathways target appetite through two mechanisms
Long-term studies confirmed sustained weight loss over two years, alongside reductions in the prevalence of prediabetes and cardiovascular risk factors (38)
Administered as a once-weekly subcutaneous injection, Mounjaro offers a treatment option for individuals whose diabetes is inadequately controlled with diet, exercise, and other oral antidiabetic medications
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doi: 10.1249/MSS.0000000000001074
A few months later the drug gained authorisation in Canada, the European Union, Japan and then Australia in 2019