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tGSH means reduced plus oxidized glutathione.) So with a whole warehouse of NADPH replenishing glutathione, NADPH reserves are perpetually high and the cell are growthy: insulin resistant
Treatment duration typically spans 4 weeks for oral supplementation protocols
Pizzorno, L
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We propose that NADH-dependent glutamate dehydrogenase activity is favoured over NADPH production to meet the immediate energy requirements of the starved wild-type cells
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